Single vs Double Lung Transplantation in Older Adults: A Propensity-Matched Analysis.

ABSTRACT:

Background

Single lung transplantation (SLT) has been shown to be associated with worse long-term outcomes than bilateral lung transplantation (BLT), but often is performed in older adults at risk of not tolerating BLT.

Research question

How do the outcomes of SLT and BLT compare among older adult recipients?

Study design and methods

The Scientific Registry of Transplant Recipients database (2005-2022) was queried for lung transplant recipients aged 65 years older. Patients were stratified by whether they underwent BLT or SLT and were propensity matched. Baseline characteristics and morbidity were compared with frequentist statistics. Survival was analyzed via Kaplan-Meier estimation. Risk factors for mortality were identified with Cox regression.

Results

Of 9,

SUBMITTER: Weingarten N 

PROVIDER: S-EPMC11867891 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature