Relationship of Pulmonary Vascular Structure and Function With Exercise Capacity in Health and COPD.

ABSTRACT:

Background

Although it is generally accepted that aerobic exercise training does not change lung structure or function, some work suggests that greater pulmonary vascular structure and function are associated with higher exercise capacity (peak rate of oxygen consumption [V˙o₂peak]).

Research question

Is there a cross-sectional association between the pulmonary vasculature and V˙o₂peak? We hypothesized that those with higher CT blood vessel volumes and pulmonary diffusing capacity for carbon monoxide (Dlco) would have higher V˙o₂peak, independent of airflow limitation.

Study design and methods

Participants from the Canadian Cohort Obstructive Lung Disease (CanCOLD) study were categorized as follows: participants with normal spirometry

SUBMITTER: Collins SE 

PROVIDER: S-EPMC11867894 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature