Comparison study of quantitative susceptibility mapping with GRAPPA and wave-CAIPI: reproducibility, consistency, and microbleeds detection.

ABSTRACT:

Purpose

We compared quantitative susceptibility mapping (QSM) with wave-CAIPI 9 × (QSM_WC9 ×) with reference standard QSM with GRAPPA 2 × (QSM_G2 ×) in two MR scanners. We also compared detectability of microbleeds in both QSMs to demonstrate clinical feasibility of both QSMs.

Materials and methods

This prospective study was approved by the institutional review board and written informed consent was obtained from each subject. Healthy subjects were recruited to evaluate intra-scanner reproducibility, inter-scanner consistency, and inter-sequence consistency of QSM_G2 × and QSM_WC9 × at 2 MR scanners. Susceptibility values measured with volume of interests (VOIs) were evaluated. Patients who were requested for susceptibility weighted imaging were also recruited in this study

SUBMITTER: Sakurama A 

PROVIDER: S-EPMC11868234 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature