Integrating myocardial CT perfusion with coronary CT angiography improves risk stratification in patients with dialysis-dependent end-stage renal disease.

ABSTRACT:

Purpose

Risk stratification for incidence of major adverse cardiovascular events (MACE) in patients with dialysis-dependent end-stage renal disease (dd-ESRD) is challenging. Moreover, the usefulness of coronary CT angiography (CCTA) is often limited because of high calcification. This study aimed to investigate the prognostic value of comprehensive cardiac CT in patients with dd-ESRD for predicting MACE.

Materials and methods

This retrospective analysis included 92 patients with dd-ESRD who underwent comprehensive cardiac CT. Obstructive coronary artery disease (CAD) was defined by CCTA with > 50% stenosis. Global myocardial blood flow (MBF) and summed stress score (SSS) were obtained through dynamic CTP. Cox regression analysis was used to assess correlation with MACE. Kapl

SUBMITTER: Araki S 

PROVIDER: S-EPMC11868328 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature