Artificial intelligence-enabled microfluidic cytometer using gravity-driven slug flow for rapid CD4⁺ T cell quantification in whole blood.

ABSTRACT: The quantification of immune cell subpopulations in blood is important for the diagnosis, prognosis and management of various diseases and medical conditions. Flow cytometry is currently the gold standard technique for cell quantification; however, it is laborious, time-consuming and relies on bulky/expensive instrumentation, limiting its use to laboratories in high-resource settings. Microfluidic cytometers offering enhanced portability have been developed that are capable of rapid cell quantification; however, these platforms involve tedious sample preparation and processing protocols and/or require the use of specialized/expensive instrumentation for flow control and cell detection. Here, we report an artificial intelligence-enabled microfluidic cytometer for rapid CD4⁺ T cel

SUBMITTER: Dixit DD 

PROVIDER: S-EPMC11868388 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature