Inverted U-shape association between urine equol levels and cancer: a national population-based cross-sectional study.

ABSTRACT: Equol, a naturally occurring phytoestrogen derived from the fermentation of soy and soy-based products by gut bacteria, is recognized for its diverse health benefits. While there is speculation about its association with cancer prevention, the scientific community has yet to reach a consensus due to the variability in research findings. Our study aims to shed light on this topic by examining the correlation between urine equol concentrations and the cancer risk among the American population. The National Health and Nutrition Examination Survey (NHANES) is a national survey of U.S. civilians in which cancer participants are enrolled in a database by a sample questionnaire. This study included 2797 Americans aged 40 years and older in the NHANES database (2005-2010). The relationship between

SUBMITTER: Li J 

PROVIDER: S-EPMC11868629 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature