Vertical transmission of hepatitis B virus in the WHO African region: a systematic review and meta-analysis.

ABSTRACT:

Background

More new infections with hepatitis B virus (HBV) occur annually in the WHO African region than in the rest of the world combined. We did a systematic review and meta-analysis to estimate the prevalence of hepatitis B surface antigen (HBsAg) in pregnant women and vertical transmission events in the region.

Methods

In this systematic review and meta-analysis, we searched PubMed, Embase, Scopus, Africa Index Medicus, and Africa Journals Online for publications between Jan 1, 1992, and Jan 7, 2024, with no language restrictions. HBsAg prevalence and vertical transmission (HBsAg positivity in children aged 6-12 months) were estimated with the use of binomial mixed models with logit links, stratified by infant vaccination status. We estimated HBsAg prevalence for subreg

SUBMITTER: Riches N 

PROVIDER: S-EPMC11868780 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature