Safety evaluation of the food enzyme 6-Phytase from the genetically modified Trichoderma reesei strain AR-766.

ABSTRACT: The food enzyme 6-Phytase (myo-inositol-hexakisphosphate 6-phosphohydrolase; EC 3.1.3.26) is produced with the genetically modified Trichoderma reesei strain AR-766 by AB Enzymes GmbH. The genetic modifications do not give rise to safety concerns. The food enzyme was considered free from viable cells of the production organism and its DNA. The food enzyme is intended to be used in four food manufacturing processes. Since residual amounts of food enzyme-total organic solids (TOS) are removed in the production of distilled alcohol, dietary exposure was calculated only for the remaining three food manufacturing processes. It was estimated to be up to 0.071 mg TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not indicate a safety concern. The system

SUBMITTER: EFSA Panel on Food Enzymes (FEZ) 

PROVIDER: S-EPMC11868782 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature