Diabetes Risks of Statin Therapy-Coenzyme Q10 May Help.

ABSTRACT:

Background

Statin therapy is associated with an increased risk of new-onset diabetes (NOD), possibly due to a reduction in coenzyme Q10 (CoQ10) levels as a result of statin use. This study aimed to investigate the relationship between exogenous CoQ10 supplementation and the development of NOD.

Methods

This study included 4394 participants from the National Health and Nutrition Examination Survey (NHANES). Baseline characteristics were compared between those with and without NOD and between those with and without CoQ10. Univariate logistic regression was performed to identify factors associated with NOD. Two models were used for confounding factors, including demographics and various covariates. Multifactor logistic regression further assessed the association between CoQ10 su

SUBMITTER: Han X 

PROVIDER: S-EPMC11868890 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature