Unveiling the prognostic value of ARID3A in breast cancer through bioinformatic analysis.

ABSTRACT:

Objective

Identifying reliable prognostic markers for breast cancer is crucial for improving survival rates and reducing mortality. Recent studies highlight the AT-rich interactive domain-containing protein (ARID) family, particularly ARID3A, as influential in cancer progression, though its specific role in breast cancer remains unclear. This study investigates ARID3A's expression, prognostic relevance, clinicopathological correlations, co-expression profiles, and protein-protein interactions in breast cancer.

Methods

ARID3A mRNA and protein expression levels were analyzed using UALCAN, GEPIA databases, and immunohistochemistry from our hospital samples. Clinical prognostic parameters and survival data were examined through bioinformatics tools, including GEPIA, Bc-GenExMine

SUBMITTER: Cai WR 

PROVIDER: S-EPMC11868939 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature