Patterns of antimicrobial use among hospitalized Veterans with and without a penicillin-class allergy.

ABSTRACT:

Objective

To explore the progress that the Veterans Health Administration has made to minimize the impact of the penicillin (PCN) allergy label, we determined the proportion of Veterans who reported a PCN-class allergy at the time of hospitalization and described antibiotic use in hospitalizations with and without a PCN-class allergy.

Design

Cross-sectional study.

Participants

National sample of 6,541,299 acute care admissions between 2011 and 2022.

Methods

We calculated the prevalence of PCN-class allergies on admission and used Poisson regression to compare patterns of antibiotic use between hospitalizations with and without a PCN-class allergy.

Results

The prevalence of PCN-class allergies on admission decreased from 12.99% to 11.20%. Use of cefazolin

SUBMITTER: Liu F 

PROVIDER: S-EPMC11869061 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature