Aspirin increases the risk of acute kidney injury in critical patients with chest trauma: a retrospective cohort study.

ABSTRACT:

Purpose

Non-steroidal anti-inflammatory drugs (NSAIDs) are increasingly utilized in trauma patients, particularly those with critical chest trauma who are susceptible to significant blood loss, leading to renal hypoperfusion. Acute kidney injury (AKI) is known to carry a poor prognosis in chest trauma patients. Therefore, investigating the potential association between NSAID use and AKI risk in critical patients with chest trauma is crucial.

Methods

We selected patients admitted to the intensive care unit (ICU) with chest trauma from the Medical Information Mart for Intensive Care III (MIMIC-III) dataset (2001-2012) and the Medical Information Mart for Intensive Care IV (MIMIC-IV) dataset (2013-2019). Propensity score matching (PSM) was used to match patients receiving NSAID

SUBMITTER: Huang Y 

PROVIDER: S-EPMC11869431 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature