Development of modified multi-parametric CT algorithms for diagnosing clear-cell renal cell carcinoma in small solid renal masses.

ABSTRACT:

Objective

To refine the existing CT algorithm to enhance inter-reader agreement and improve the diagnostic performance for clear-cell renal cell carcinoma (ccRCC) in solid renal masses less than 4 cm.

Methods

A retrospective collection of 331 patients with pathologically confirmed renal masses were enrolled in this study. Two radiologists independently assessed the CT images: in addition to heterogeneity score (HS) and mass-to-cortex corticomedullary attenuation ratio (MCAR), measured parameters included ratio of major diameter to minor diameter at the maximum axial section (Major axis / Minor axis), tumor-renal interface, standardized heterogeneity ratio (SHR), and standardized nephrographic reduction rate (SNRR). Spearman's correlation analysis was performed to evaluate th

SUBMITTER: Jin P 

PROVIDER: S-EPMC11869432 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature