Impact of maternal COVID-19 infection on offspring immunity and maternal-fetal outcomes at different pregnancy stages: a cohort study.

ABSTRACT:

Objective

To investigate the impact of COVID-19 infection on maternal and neonatal outcomes and immunity in pregnant women in China.

Methods

283 pregnant women with COVID-19 were included in the prospective observational cohort study and divided into five groups based on infection stage. Antibody levels were measured in plasma, umbilical cord blood, and breast milk, and combined with clinical data and 6-month follow-up results. We measured SARS-CoV-2 antibody levels using a chemiluminescence immunoassay and analyzed the data with the Kruskal-Wallis test, χ2 test, or Fisher's exact test.

Results

No significant differences were found in age, BMI, weight change during pregnancy, or the incidence of gestational hypertension, gestational diabetes, gestational hypothyroidis

SUBMITTER: Sun Y 

PROVIDER: S-EPMC11869480 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature