Examining breast cancer screening recommendations in Canada: The projected resource impact of screening among women aged 40-49.

ABSTRACT:

Objective

To quantify the resource use of revising breast cancer screening guidelines to include average-risk women aged 40-49 years across Canada from 2024 to 2043 using a validated microsimulation model.

Setting

OncoSim-Breast microsimulation platform was used to simulate the entire Canadian population in 2015-2051.

Methods

We compared resource use between current screening guidelines (biennial screening ages 50-74) and alternate screening scenarios, which included annual and biennial screening for ages 40-49 and ages 45-49, followed by biennial screening ages 50-74. We estimated absolute and relative differences in number of screens, abnormal screening recalls without cancer, total and negative biopsies, screen-detected cancers, stage of diagnosis, and breast cance

SUBMITTER: Basmadjian RB 

PROVIDER: S-EPMC11869510 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature