The association between insulin resistance and QT interval: A systematic review and Meta-Analysis.

ABSTRACT:

Background

Insulin resistance (IR) is a major health concern associated with various diseases, and prolonged QT interval can potentially lead to life-threatening arrhythmias and death. There are conflicting views on the relationship between IR and QT interval. This meta-analysis aims to comprehensively investigate the association between IR and QT interval.

Methods

An extensive search in databases PubMed, Scopus, Cochrane Library, Embase, and Web of Science up to October 2024 was conducted. Cohort studies which reported means and standard deviations for the QTc interval across the case and control groups with and without insulin resistance based on HOMA-IR were eligible for inclusion. Research with partial or inaccessible primary data, those involving participants with pre-e

SUBMITTER: Mobasheri-Shiri M 

PROVIDER: S-EPMC11869589 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature