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Predictors of long-term outcome of patients with schizophrenia in Africa: systematic review and meta-analysis.


ABSTRACT:

Background

One of the most compelling areas of schizophrenia research involves the investigation of its longitudinal course and clinical outcomes. Longitudinal studies have provided profound insights into the trajectory of schizophrenia, elucidating its progression, clinical phenotype, functional impairments, treatment responsiveness, and key prognostic determinants. While contemporary therapeutic interventions have demonstrated promise in altering disease trajectory and enhancing recovery, schizophrenia remains characterized by heterogeneous outcomes, distinguishing it from other psychotic disorders. This review aims to assess the pooled prevalence of positive outcomes and identify key predictors on individuals with schizophrenia disorder across Africa.

Methods

A comprehens

SUBMITTER: Kelebie M 

PROVIDER: S-EPMC11869747 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature