Yellow light and ultrasound Dual-responsive strontium-doped zinc oxide composites for dental caries prevention and remineralization.
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ABSTRACT: Dental caries is one of the most prevalent chronic infectious diseases, mainly due to acid production by bacteria in the plaque biofilm, leading to enamel demineralization, tooth defects and pulpitis. Most of the current treatments are invasive and do not combine restoration of dental tissues, resolution of tooth staining or prevention of dental caries. In this study, a polydopamine (PDA)-encapsulated strontium-doped zinc oxide composite (Sr-ZnO@PDA, denoted as SZ@PDA) has been developed for caries prevention and remineralization. The PDA wrapping endows SZ@PDA with a narrow energy band gap (1.78 eV), which can simultaneously respond to yellow light (YL) with favorable biosafety and ultrasound (US) with high tissue penetration. The synergistic piezo-photocatalytic action of YL and US with
SUBMITTER: Mu Y
PROVIDER: S-EPMC11869965 | biostudies-literature | 2025 May
REPOSITORIES: biostudies-literature
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