Isolation, characterization and genomic analysis of bacteriophages for biocontrol of vibriosis caused by Vibrio alginolyticus.

ABSTRACT: Vibrio alginolyticus is a significant opportunistic pathogen in marine environments, affecting both marine organisms and humans. The rise of antibiotic-resistant strains has prompted the exploration of bacteriophages as alternative biological control agents. In this study, 414 lytic bacteriophages specific to V. alginolyticus were isolated from various seafood and environmental samples. Phages P122, P125, and P160 demonstrated the broadest host range, effectively lysing 79.01 % of fish pathogenic V. alginolyticus strains and 44.69 % of environmental strains. However, no activity was observed against clinical V. alginolyticus strains or other tested species, including V. harveyi, Escherichia coli, Staphylococcus aureus, and Aeromonas hydrophila. One-step growth curve analysis revealed laten

SUBMITTER: Chaichana N 

PROVIDER: S-EPMC11870190 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature