Changes in the distribution of the tear film lipid layer after intensive pulsed light combined with meibomian gland expression in patients with meibomian gland dysfunction.

ABSTRACT:

Purpose

This study aimed to investigate changes in dry eye disease (DED) parameters and tear film lipid layer distribution after intensive pulse light (IPL) combined with meibomian gland expression (MGX) in patients with meibomian gland dysfunction (MGD).

Methods

This retrospective study included 218 patients diagnosed with MGD who underwent IPL combined with MGX. Various DED parameters, including tear film lipid layer thickness (LLT), were measured using a Placido disc tear film analyzer and slit lamp. Inferior corneal images were quantified and divided into upper, lower, nasal, and temporal quadrants, with further subdivision into six parts from top to bottom using Python.

Results

The ocular surface disease index, meibomian gland expressibility, and quality scores s

SUBMITTER: Lee Y 

PROVIDER: S-EPMC11870382 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature