Paclitaxel-loaded elastic liposomes synthesised by microfluidics technique for enhance transdermal delivery.

ABSTRACT: The inherent flexibility of elastic liposomes (EL) allows them to penetrate the small skin pores and reach the dermal region, making them an optimum candidate for topical drug delivery. Loading chemotherapy in ELs could improve chemotherapy's topical delivery and localise its effect on skin carcinogenic tissues. Chemotherapy-loaded EL can overcome the limitations of conventional administration of chemotherapies and control the distribution to specific areas of the skin. In the current studies, Paclitaxel was utilised to develop Paclitaxel-loaded EL. As an alternative to the conventional manufacturing methods of EL, this study is one of the novel investigations utilising microfluidic systems to examine the potential to enhance and optimise the quality of Els by the microfluidics method. The

SUBMITTER: Jaradat E 

PROVIDER: S-EPMC11870984 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature