Longitudinal Trajectories of Antidiabetic Medication Adherence Over 5 Years From Treatment Initiation-A Swedish Nationwide Cohort Study.

ABSTRACT: Patients' longitudinal adherence to antidiabetic medication in routine clinical care remains unexplored. This study aimed to identify adherence groups among individuals with type 2 diabetes with up to 1 and 5 years of follow-up. This was a register-based cohort study using data from Swedish national health and population registers and the National Diabetes Register (2006-2022). New users of blood glucose-lowering drugs (other than insulin) were identified. Trajectories of the proportion of days covered (PDC) by any antidiabetic medication, including insulin, over 1- and 5-year periods were clustered using k-means for longitudinal data. Analyses up to 1- and 5-year follow-up periods included 75,421 individuals with an overall mean PDC of 0.7 and 283,795 individuals with an overall mean PDC

SUBMITTER: Pazzagli L 

PROVIDER: S-EPMC11871106 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature