Development of a novel calculator to predict gonadotropin dose and oocyte yield in oocyte cryopreservation cycles.

ABSTRACT:

Purpose

To develop a predictive model for estimating the total dose of gonadotropins and the number mature oocytes in planned oocyte cryopreservation cycles.

Methods

In this retrospective study, oocyte cryopreservation cycles recorded in the Society for Assisted Reproductive Technology Clinic Outcome Reporting System Database from 2013 to 2018 were analyzed. Bivariate copula additive models for location, scale, and shape were performed to create a predictive model for estimating total dose of gonadotropins and number of mature oocytes.

Results

A total of 15,806 oocyte cryopreservation cycles between 2013 and 2018 were included in the analysis. The average age of participants was 35.4 years, the mean duration of stimulation was 11.8 days, and the average number of matu

SUBMITTER: Yilmaz BD 

PROVIDER: S-EPMC11871197 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature