Prolactin levels and chronic kidney disease and the subsequent risk of cardiovascular events: A long term population based cohort study.

ABSTRACT: Both the clearance and secretion of prolactin are disrupted in chronic kidney disease (CKD). Evidence indicates that prolactin may play a role in cardiovascular (CV) disturbances. Considering the increased cardiovascular risk associated with CKD, this study investigates the relationship between prolactin levels, CKD, and the risk of CV events in both women and men, with an average follow-up period of 20 years. The study included 2,005 participants from the Tehran Lipid and Glucose Study (TLGS) who met the inclusion criteria. They were reassessed approximately every three years for a median follow-up of 19.0 years (Interquartile range (IQR):16.4-20.2), during which occurrences of CKD and CV events were recorded. A pooled logistic regression model examined the influence of Prolactin on CV ev

SUBMITTER: Rojhani E 

PROVIDER: S-EPMC11871319 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature