Association of constipation with all-cause mortality among individuals with type 2 diabetes: A retrospective cohort study.

ABSTRACT:

Background

Constipation is a common complication in type 2 diabetes mellitus (T2DM), yet its impact on mortality remains unclear. This study aimed to investigate the association between constipation and all-cause mortality in patients with T2DM.

Methods

We conducted a retrospective cohort study using data from the National Health and Nutrition Examination Survey (NHANES) 2005-2010. Mortality outcomes were ascertained through linkage to National Death Index records until December 31, 2019. The association between constipation and all-cause mortality was assessed using weighted Cox proportional hazards regression models. Kaplan-Meier curves were then employed to visualize survival probabilities. Effect modification was explored through stratified analyses and interaction tests

SUBMITTER: Li X 

PROVIDER: S-EPMC11871400 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature