Race-Specific and Race-Neutral Equations for Lung Function and Asthma Diagnosis in Black Children.

ABSTRACT:

Importance

Use of the race-neutral Global Lung Initiative (GLI) equation has been shown to generate decreased lung function measures in Black children and adults. The effect on asthma detection and diagnosis in children is unknown.

Objective

To compare the use of race-specific vs race-neutral equations on subsequent asthma diagnosis in children.

Design, setting, and participants

The Childhood Asthma Management Program (CAMP, 1991-2012), the Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS, 2001-2010), and the Mechanisms of Progression from Atopic Dermatitis to Asthma (MPAACH, 2016-2024) cohorts were included in this cohort study. Children in the CAMP cohort were aged 5 to 12 years with mild to moderate asthma. The CCAAPS and MPAACH cohorts included infants

SUBMITTER: Chang WC 

PROVIDER: S-EPMC11871546 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature