Molecular epidemiology of Escherichia coli in bloodstream infections from a general hospital in Ningxia, China, 2022-2023.

ABSTRACT:

Objective

To analyse the antibiotic resistance, resistance genes and clonal relationship of Escherichia coli in bloodstream infections in Ningxia from 2022 to 2023.

Methods

We retrospectively analyzed the antibiotic susceptibilities of 257 isolates. PCR was used to detect bla_TEM, bla_SHV, bla_CTX-M, qnrS, qnrA, qnrB, oqxA, qepA, gyrA, gyrB, parC, and parE, and the clonal relationship through multilocus sequence typing (MLST).

Results

One hundred and twenty-nine of 257 patients were male (50.2%). The 257 E. coli isolates were mainly obtained from the Emergency, Hepatobiliary Surgery, and Haematology Departments, accounting for 56.6%, 7.3%, and 6.2%, respectively. There is no significant difference in sex and genes between the two groups o

SUBMITTER: Hu X 

PROVIDER: S-EPMC11871600 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature