Tumor ADC value predicts outcome and yields refined prognostication in uterine cervical cancer.

ABSTRACT: Pelvic MRI is essential for evaluating local and regional tumor extent in uterine cervical cancer (CC). Tumor microstructure captured by diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) markers may be closely linked to prognosis in CC.Purpose To explore whether primary tumor ADC markers predict survival in CC.Material and methods CC patients (n = 179) diagnosed during 2009-2020 with MRI-assessed primary maximum tumor_size ≥ 2 cm were included in this retrospective single-center study. Two radiologists read all MRIs independently, measuring mean tumor ADC values in manually drawn regions of interest (ROIs) and mean tumor ADC (tumor_ADCmean) from five measurements for the two readers was used. ADC from ROIs in the myometrium (myometrium_ADC

SUBMITTER: Lura N 

PROVIDER: S-EPMC11871606 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature