Effect of prone position on ventilation-perfusion matching in patients with moderate to severe ARDS with different clinical phenotypes.

ABSTRACT:

Background

ARDS is a heterogeneous syndrome involving different subphenotypes with different clinical features and different responses to treatment strategies. The prone position (PP) is an effective treatment for ARDS; however, whether the effects of prone positioning vary among ARDS patients with different subphenotypes remains unknown.

Objectives

To evaluated the impact of PP on ventilation-perfusion matching(VQ matching) by contrast-enhanced Electrical impedance tomography (EIT) in ARDS patients with different subphenotypes.

Methods

This was a prospective, observational study at the medical ICU of Zhongda Hospital, Southeast University. ARDS patients undergoing mechanical ventilation were screened and allocated to different subphenotypes based on lung morphology (

SUBMITTER: Yang S 

PROVIDER: S-EPMC11871685 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature