A retrospective study of the association between serum uric acid and risk of coronary heart disease complicated with different types of chronic heart failure.

ABSTRACT: Heart failure (HF) is a terminal stage of cardiovascular diseases, classified based on ejection fraction. Serum uric acid (SUA) has been implicated in the pathogenesis and progression of coronary artery disease (CAD) with HF, yet its predictive value remains unclear. This study aimed to evaluate the predictive role of SUA in the progression of HF in CAD patients and its potential to differentiate HF types. A retrospective analysis was conducted on 342 CAD patients, including 29 with CAD alone and 313 with CAD complicated by varied HF types. Biochemical parameters and HF severity were assessed, and logistic regression analyses were performed to identify independent predictors of HF progression. Significant differences were observed in biochemical parameters, including glutamic-pyruvic trans

SUBMITTER: Yu L 

PROVIDER: S-EPMC11871693 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature