Haloperidol for the treatment of delirium in ICU patients: a systematic review and meta‑analysis.

ABSTRACT:

Objectives

Haloperidol is the most frequently prescribed medication for managing delirium in the intensive care unit (ICU). However, there is limited and inconclusive evidence regarding its efficacy. A meta-analysis was conducted by pooling data from recent clinical randomized controlled trials to assess the effectiveness of haloperidol in adult ICU patients with delirium.

Methods

Studies were searched in PubMed, Embase and Cochrane Library databases on August 10, 2024. We performed a meta-analysis to estimate the efficacy of haloperidol for the treatment of ICU adult patients with delirium. This study is registered with INPLASY, number 202480104. The estimates are expressed as odds ratio (OR) or mean difference (MD) with a 95% confidence interval (CI).

Results

A tota

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC11871728 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature