Ambient air pollution does not diminish the beneficial effects of active commuting on heart failure: a prospective study in UK Biobank.

ABSTRACT:

Background

Evidence on active commuting and heart failure (HF) under levels of air pollution exposure is limited, and little is known on the potential mediation roles of inflammation. The objective of this study was to investigate the association between active commuting and HF, as well as to ascertain whether air pollution may influence this relationship.

Methods

This prospective study included 241,786 participants without HF at baseline in UK Biobank. The commuting mode was recorded using questionnaire. We examined long-term exposure to air pollution, including particulate matter with an aerodynamic diameter smaller than 2.5 μm (PM_2.5) or 10 μm (PM₁₀), PM_2.5-10, nitrogen dioxide (NO₂), and nitrogen oxide (NO_x). The inc

SUBMITTER: Sun Q 

PROVIDER: S-EPMC11871780 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature