Procalcitonin use in febrile children attending European emergency departments: a prospective multicenter study.

ABSTRACT:

Background

Studies on procalcitonin (PCT) for identifying sepsis were published as early as 1993 and since then, PCT has been the topic of over 8,500 studies. Several studies show PCT to be superior to CRP in differentiating invasive infections such as sepsis from viral infections, especially early in the disease course. However, its actual use in clinical practice is poorly documented. Our aim was to study the use of PCT in febrile children attending the ED across Europe and compare this to the use of CRP.

Methods

The MOFICHE/PERFORM study, a prospective multicenter study, took place at 12 European EDs in eight countries and included febrile children < 18 years. In this secondary analysis of nine participating EDs that used PCT, descriptive analyses were performed, describi

SUBMITTER: Borensztajn DM 

PROVIDER: S-EPMC11871781 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature