Safety and Feasibility of Peanut, Tree Nut, and Sesame Oral Immunotherapy in Infants and Toddlers in a Real-World Setting.

ABSTRACT:

Background

Oral immunotherapy (OIT) for food allergy has been largely studied in older children within the context of clinical trials, and its availability has historically been limited for younger patients with food allergy. Data have shown that the most impact may actually be seen with the use of OIT in younger infants and toddlers.

Objective

To evaluate the safety and feasibility of OIT in subjects 24 months and younger in a real-world setting using commercially available food products.

Methods

This was a retrospective study of subjects 24 months and younger initiated on OIT for peanut, tree nut, or sesame allergy within the Scripps Clinic allergy department. Medical records were reviewed for data regarding initial oral food challenges, OIT, and adverse outcomes.

SUBMITTER: Huang J 

PROVIDER: S-EPMC11872170 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature