Beat-to-beat variability of aortic pulse wave velocity: implications for aortic stiffness measurements.

ABSTRACT:

Objectives

Aortic pulse wave velocity (aPWV) predicts cardiovascular risk. Being the reference method for aortic stiffness evaluation, invasive aPWV is also recommended for validation of noninvasive devices. Because of intrinsic haemodynamic variability and processing issues, aPWV shows beat-to-beat variability. We aimed to quantify this variability and evaluate its implications for the reliability and use of aPWV as reference in validation and clinical application studies.

Methods

The study included n  = 84 patients, in whom two datasets of invasive data were recorded: 1) simultaneous ascending aorta and iliac pressure acquisitions using a dual-tip intra-aortic catheter, and 2) an additional ascending aorta pressure acquisition. By combining the iliac and ascending aorta pr

SUBMITTER: Giudici A 

PROVIDER: S-EPMC11872263 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature