Associations between multimorbidity burden and objective and patient-reported sleep outcomes among people with HIV.

ABSTRACT:

Background

We aimed to provide insights into the effects of comorbidities on sleep health in people with HIV by assessing associations between multimorbidity patterns and sleep outcomes in the Pharmacokinetic and clinical Observations in PeoPle over fiftY (POPPY) sub-study.

Methods

Principal component analysis identified six multimorbidity patterns among participants with HIV ( n  = 1073) at baseline: cardiovascular diseases (CVDs), sexually transmitted diseases, metabolic, mental/joint, neurological and cancer/other. Burden z scores were calculated for each individual/pattern. A subset of 478 participants completed sleep assessments at follow-up, including questionnaires [Insomnia Severity Index (ISI), Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep

SUBMITTER: Sukumaran L 

PROVIDER: S-EPMC11872264 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature