Adrenaline for traumatic cardiac arrest: A post hoc analysis of the PARAMEDIC2 trial.

ABSTRACT:

Introduction

There is controversy about the effectiveness of adrenaline in traumatic cardiac arrest. This study reports the patient characteristics and outcomes of adults with trauma-related out of hospital cardiac arrest treated with adrenaline or placebo.

Methods

This post-hoc, sub-group analysis of the Pre-hospital Randomised Assessment of Adrenaline in Cardiac Arrest-2 (PARAMEDIC-2) trial explored the effect of adrenaline on survival to hospital admission, longer-term survival and neurological outcomes amongst adults with trauma related out of hospital cardiac arrest. Individual patients were randomised through opening a single treatment pack which contained either 10 doses of 1 mg adrenaline or 0.9% saline placebo. Treating clinicians, investigators, outcome assessors a

SUBMITTER: Ji C 

PROVIDER: S-EPMC11872399 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature