Impacts of Curcumin Supplementation on Cardiometabolic Risk Factors in Patients With Polycystic Ovary Syndrome: A Systematic Review and Dose-Response Meta-Analysis.

ABSTRACT:

Background and aim

Patients with polycystic ovary syndrome (PCOS) commonly have cardiometabolic risk factors. Oxidative stress (OS) significantly contributes to the development of cardiometabolic diseases. Curcumin (CUR) exhibits antioxidant properties that aid in OS regulation. This systematic review and dose-response meta-analysis of randomized clinical trials (RCTs) evaluated the effects of CUR supplementation on cardiometabolic risk factors in women with PCOS.

Methods

A systematic search across various databases was implemented to identify eligible RCTs published until January 2024. A meta-analysis was conducted employing a random-effects model.

Results

Eight RCTs were included in the meta-analysis. It was indicated that CUR supplementation substantially reduced f

SUBMITTER: Mohammadi S 

PROVIDER: S-EPMC11872691 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature