Taste impairment in patients with Parkinsonism.

ABSTRACT:

Background

Taste impairment is a prevalent issue among individuals with idiopathic Parkinson's disease (iPD). However, understanding taste disorders among different Parkinsonism remains incomplete. Our objective was to assess the incidence and severity of taste responses to sweet, salty, sour, bitter, and umami substances in patients with iPD, progressive supranuclear palsy (PSP), and multiple system atrophy (MSA).

Methods

Taste function was evaluated by assessing the intensity ratings of four concentrations of sweet, salty, sour, bitter, and umami in 221 healthy controls (HCs), 251 iPD patients, 156 PSP patients, and 60 MSA patients. The Kruskal-Wallis one-way analysis was employed to discern differences in taste function among groups. Logistic regression models were utiliz

SUBMITTER: Zhu Q 

PROVIDER: S-EPMC11872754 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature