Seroprevalence of <i>Getah virus</i> in pigs in Southeast China determined with a recombinant Cap protein-based indirect ELISA.

ABSTRACT: Getah virus (GETV) is a mosquito-borne virus with a broad host range, including mosquitoes and various animals such as pigs, horses, goats, cattle, boars, and blue foxes. In pigs, GETV can cause fever, abortion and reproductive disorders in sows, as well as fever, tremors, and diarrhea in piglets, posing a serious threat to the pig production industry. However, there are few reports on the epidemiology of GETV in China, and reliable diagnostic kits for large-scale detection of GETV antibodies are lacking. Therefore, this study aimed to establish a rapid, sensitive and suitable GETV antibody detection assay for clinical detection. We expressed the recombinant protein Cap in Escherichia coli by constructing a recombinant plasmid, pET-32a-Cap, which contained a His tag and the G

SUBMITTER: Lan J 

PROVIDER: S-EPMC11872902 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature