Mutations in the voltage-gated sodium channel associated with permethrin resistance in Rhipicephalus linnaei populations in Thailand.

ABSTRACT: Insecticide resistance is a serious threat to vector control programs worldwide. Therefore, it is crucial to monitor the development of resistance in vector populations. Rhipicephalus linnaei (Audouin, 1826) is a cosmopolitan tick and a vector of medically important pathogens. We conducted a comprehensive investigation of permethrin resistance in larvae of Rh. linnaei populations across Thailand by comparing phenotypic resistance with tick genotypes, focusing on mutations in Domain II and III of the voltage-gated sodium channel gene. Results showed that larvae obtained from engorged female tick populations in Thailand have developed resistance to permethrin, with levels varying by location. Resistance ratios ranged from 1 to 56 when compared to the least susceptible local population. Genot

SUBMITTER: Takhampunya R 

PROVIDER: S-EPMC11873048 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature