New insights into changes in ocular structural parameters in simulated hypobaric hypoxia.

ABSTRACT:

Purpose

High altitude is the main area for human exploration, and human eye is an important organ for obtaining visual signals. The changes of ocular structural parameters in a simulated hypobaric hypoxia environment need to be clarified.

Methods

Measurements were taken at five altitudes ((1) ground, (2) 3500 m, (3) 4000 m, (4) 4500 m and (5) ground). Refractive values were measured with the IOL Master (Carl Zeiss Shanghai Co. Ltd.). Data analysis was performed using the Kolmogorov-Smirnov (K-S) test, paired sample T-test and Wilcoxon test.

Results

Subjects' axial length (AL) increased with altitude, peaking at 4500 m, then decreased. Significant AL differences were observed across altitudes (p<0.05), except between 2-5 and 3-5. Central corneal thickness (CCT) thicken

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11873329 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature