Development of a diagnostic checklist to identify functional cognitive disorder versus other neurocognitive disorders.

ABSTRACT:

Background

Functional cognitive disorder (FCD) poses a diagnostic challenge due to its resemblance to other neurocognitive disorders and limited biomarker accuracy. We aimed to develop a new diagnostic checklist to identify FCD versus other neurocognitive disorders.

Methods

The clinical checklist was developed through mixed methods: (1) a literature review, (2) a three-round Delphi study with 45 clinicians from 12 countries and (3) a pilot discriminative accuracy study in consecutive patients attending seven memory services across the UK. Items gathering consensus were incorporated into a pilot checklist. Item redundancy was evaluated with phi coefficients. A briefer checklist was produced by removing items with >10% missing data. Internal validity was tested using Cronbach'

SUBMITTER: Cabreira V 

PROVIDER: S-EPMC11873336 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature