Lymphatic filariasis transmission 10 years after stopping mass drug administration in the Gomoa west district of Ghana.

ABSTRACT:

Objectives

A survey was conducted 10 years after stopping MDA in the Gomoa West District of Ghana to assess the Wuchereria bancrofti prevalence in both human and mosquito populations.

Methods

In seven communities, infection in humans was assessed using the filariasis test strip (FTS). Mosquitoes were collected once a month over six months using pyrethrum spray catches (PSC). The mosquitoes were analyzed for W. bancrofti infections, using dissection followed by poolscreening PCR.

Results

FTS results showed that 2/524 (0.38%; 95% CI, 0.0%-0.9%) individuals tested positive for antigen. Dissections revealed W. bancrofti infections in 5/107 Anopheles gambiae (4.7%: 95% CI, 2.2-8.5) from one community, with three mosquitoes harboring L3 larvae (2.8%: 95% CI, 0.9-7.5). PCR a

SUBMITTER: Boateng CA 

PROVIDER: S-EPMC11873683 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature