Bio2Byte Tools deployment as a Python package and Galaxy tool to predict protein biophysical properties.

ABSTRACT:

Summary

We introduce a unified Python package for the prediction of protein biophysical properties, streamlining previous tools developed by the Bio2Byte research group. This suite facilitates comprehensive assessments of protein characteristics, incorporating predictors for backbone and sidechain dynamics, local secondary structure propensities, early folding, long disorder, beta-sheet aggregation, and fused in sarcoma (FUS)-like phase separation. Our package significantly eases the integration and execution of these tools, enhancing accessibility for both computational and experimental researchers.

Availability and implementation

The suite is available on the Python Package Index (PyPI): https://pypi.org/project/b2bTools/ and Bioconda: https://bioconda.github.io/recipes/b2

SUBMITTER: Gavalda-Garcia J 

PROVIDER: S-EPMC11873786 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature