Twenty-four-hour urine oxalate and risk of chronic kidney disease.

ABSTRACT:

Background

To assess whether 24-h urine oxalate (UOx) excretion is a risk factor for incident chronic kidney disease (CKD).

Methods

This longitudinal observational USA-based study included 426 896 individuals aged ≥18 years with no CKD at baseline and with at least one UOx, and at least 6 months of baseline and 6 months of follow-up data. Of these, 11 239 (2.6%) had an underlying malabsorptive condition. Incident CKD, defined by relevant International Classification of Diseases codes, was identified from a multi-source data cloud containing individual-level healthcare claims and electronic medical records data. The association between categories of UOx and incident CKD was modeled using logistic regression adjusting for age, sex, race, body mass index, baseline urine calcium

SUBMITTER: Puurunen M 

PROVIDER: S-EPMC11873791 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature