Exploration of the quantitative-effectiveness association between acupuncture temporal parameters and chemotherapy-induced peripheral neuropathy in cancer patients: a dose-response meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Chemotherapy-induced peripheral neuropathy (CIPN) is one of the commonly reported symptoms impacting cancer survivors. This study evaluated and compared the effectiveness of acupuncture treatments for CIPN.

Methods

We searched six databases from their inception to August 2024 to identify eligible randomized controlled trials (RCTs). Primary outcome were pain scores. Secondary outcomes were quality of life including FACT/GOG-Ntx and EORTC QLQ-C30. The robust error meta-regression (REMR) method was used to evaluate the dose-response relationship across treatment parameters, including number of sessions, frequency, and duration.

Results

In total, 11 RCTs featuring 740 participants were included. The meta-analysis demonstrated that the primary analysis achieved

SUBMITTER: Tian H 

PROVIDER: S-EPMC11873836 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature