Engineering and application of multiepitope recombinant proteins to enhance resistance to <i>Botrytis cinerea</i> in tomatoes: a new paradigm for creating plant immune activators.

ABSTRACT: Plant elicitors have emerged as key agents in effectively invoking immune responses across various plant species, gaining attention for their role in sustainable agricultural protection strategies. However, the economic utility of peptide elicitors such as flg22, flgII-28, and systemin is limited when considering broader agricultural applications. This study introduces a novel recombinant protein, SlRP5, which integrates five active epitopes-flg22, csp22, flgII-28, SIPIP1, and systemin-to activate immune responses and significantly enhance resistance to Botrytis cinerea in tomatoes (Solanum lycopersicum). SIRP5 significantly induced reactive oxygen species (ROS), MAPK activation, and callose deposition in tomato leaves during in vitro experiments. Transcriptomic analys

SUBMITTER: Man X 

PROVIDER: S-EPMC11873852 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature