A Molecularly Imprinted Polymer-Based Porous Silicon Optical Sensor for Quercetin Detection in Wines.

ABSTRACT: Quercetin (QU), a bioactive flavonoid with significant nutritional and antioxidant properties, plays a vital role in the quality and stability of wine. This study presents the development of a molecularly imprinted polymer (MIP)-based optical sensor for the selective and sensitive detection of quercetin in red and white wines. The sensor combines the selective molecular recognition capabilities of MIPs with the optical properties of nanostructured porous silica (PSiO₂) scaffolds, which serve as the transducer. MIP synthesis was achieved through a novel room-temperature vapor-phase polymerization method using pyrrole as the functional monomer. Computational simulations were used to optimize pyrrole interactions with QU and at the polymer level, to explore the binding interactions

SUBMITTER: Di Giulio T 

PROVIDER: S-EPMC11873946 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature