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Mechanical Circulatory Support With Impella in High-Risk Patients With Chronic Total Occlusion and Complex Multivessel Disease.


ABSTRACT:

Background

The therapeutic management of patients with multivessel disease and severe left ventricular dysfunction is complex and controversial.

Aims

The aim of this study was to analyze the clinical outcomes and the changes in left ventricular ejection fraction (LVEF) in patients with severe left ventricular dysfunction and at least one chronic total occlusion (CTO) undergoing percutaneous coronary intervention (PCI) with hemodynamic support provided by Impella.

Methods

Retrospective, multicenter study enrolling patients with severe left ventricular dysfunction and severe coronary artery disease with at least one CTO who required percutaneous mechanical circulatory support with Impella, from January 2019 to December 2023. The primary endpoints were the incidence of M

SUBMITTER: Gallo I 

PROVIDER: S-EPMC11874245 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature